Oral Communications

We examine the intersection of personalizing medicines and network pharmacology to identify strategies for the development of therapies that are fully informed by both concepts. Current approaches to personalizing medicines have benefited from the development of new diagnostics that enable more effective treatment selection for cohorts or individuals. The concept of network pharmacology is less familiar but may be defined as seeking to describe therapeutically beneficial and adverse drug reaction outcomes of medicines in terms of the molecular interaction of drugs with several inter-related proteins or networks. Crucially this differs from the traditional one target – one drug model that continues to dominate classic medicinal chemistry thinking.