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Delayed Access to Alcohol Accelerates Self‐Administration of Alcohol on a Progressive Ratio Schedule
Author(s) -
Pickering Chris,
Moreira Tiago,
Liljequist Sture
Publication year - 2007
Publication title -
basic and clinical pharmacology and toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.805
H-Index - 90
eISSN - 1742-7843
pISSN - 1742-7835
DOI - 10.1111/j.1742-7843.2006.00002.x
Subject(s) - alcohol , ethanol , schedule , self administration , alcohol consumption , medicine , anesthesia , reinforcement , liquid diet , psychology , chemistry , computer science , biochemistry , social psychology , operating system
In a previous report, we found that a 5‐min. delay in alcohol access increases ethanol intake in rats trained to self‐administer 5% ethanol. To assess the effects of this delay on the motivation to self‐administer ethanol, Wistar rats were trained on a progressive ratio schedule of reinforcement and presented with the 5‐min. delay. There was no change in break point (6 presses/delivery), active (125 presses/30 min.) or inactive (10 presses/30 min.) lever presses after the 5‐min. delay compared to baseline. However, response cessation occurred 10 min. earlier in this delay session compared to baseline indicating that consumption was accelerated by delayed access to alcohol.