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Long‐Term Parathyroid‐ and c‐Cell Function after Radioiodine for Benign Thyroid Diseases
Author(s) -
Mortensen Lene S.,
Smidt Kamille,
Jørgensen Anette,
Nielsen Jørn Theil,
Laurberg Peter,
Søndergaard Liselotte,
Rungby Jørgen
Publication year - 2005
Publication title -
basic and clinical pharmacology and toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.805
H-Index - 90
eISSN - 1742-7843
pISSN - 1742-7835
DOI - 10.1111/j.1742-7843.2005.pto_97104.x
Subject(s) - term (time) , thyroid , medicine , thyroid function , endocrinology , physics , quantum mechanics
The study examined static and dynamic parathyroid hormone and calcitonin secretion after radioiodine, and was a retrospective study of patients having received radioiodine for benign conditions 8–12 years earlier. In one group of patients parathyroid hormone and calcium were measured as single blood tests, in a second group of patients parathyroid hormone and calcitonin secretion capacity were measured during a hypocalcaemic citrate‐clamp and a hypercalcaemic stimulation test. Baseline calcium and parathyroid hormone were normal within expected ranges 8–12 years after radioiodine. Stimulated parathyroid hormone or calcitonin secretion did not differ from an age‐ and gender‐matched control group. Radioiodine in doses used for benign thyroid diseases appears safe with regard to parathyroid hormone and calcitonin secretion.