Premium
New Mathematical Methods in Pharmacokinetic Modeling
Author(s) -
?urišová Mária,
Dedík Ladislav
Publication year - 2005
Publication title -
basic and clinical pharmacology and toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.805
H-Index - 90
eISSN - 1742-7843
pISSN - 1742-7835
DOI - 10.1111/j.1742-7843.2005.pto_01.x
Subject(s) - computer science , pharmacokinetics , management science , mathematical model , perspective (graphical) , artificial intelligence , mathematics , pharmacology , engineering , medicine , statistics
In recent years, several new methods for the mathematical modeling have gradually emerged in pharmacokinetics, and the development of pharmacokinetic models based on these methods has become one of the most rapidly growing and exciting application‐oriented sub‐disciplines of the mathematical modeling. The goals of our MiniReview are twofold: i) to briefly outline fundamental ideas of some new modeling methods that have not been widely utilized in pharmacokinetics as yet, i.e. the methods based on the following concepts: linear time‐invariant dynamic system, artificial‐neural‐network, fuzzy‐logic, and fractal; ii) to arouse the interest of pharmacological, toxicological, and pharmaceutical scientists in the given methods, by sketching some application examples which indicate the good performance and perspective of these methods in solving pharmacokinetic problems.