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Preliminary Study of the in vitro Interaction between Alcohol, High‐Dose Flunitrazepam and its Three Metabolites using Human Liver Microsomes
Author(s) -
Tanaka Einosuke,
Nakamura Takako,
Terada Tasaru,
Shinozuka Tatsuo,
Honda Katsuya
Publication year - 2005
Publication title -
basic and clinical pharmacology and toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.805
H-Index - 90
eISSN - 1742-7843
pISSN - 1742-7835
DOI - 10.1111/j.1742-7843.2005.pto960113.x
Subject(s) - flunitrazepam , triazolam , metabolite , pharmacology , drug , cyp3a4 , chemistry , pharmacokinetics , benzodiazepine , drug metabolism , microsome , demethylation , cytochrome p450 , medicine , metabolism , biochemistry , enzyme , receptor , gene expression , dna methylation , gene