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Review article: Efficacy and safety of methoxyflurane analgesia in the emergency department and prehospital setting
Author(s) -
Grindlay Joanne,
Babl Franz E
Publication year - 2009
Publication title -
emergency medicine australasia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.602
H-Index - 52
eISSN - 1742-6723
pISSN - 1742-6731
DOI - 10.1111/j.1742-6723.2009.01153.x
Subject(s) - methoxyflurane , medicine , analgesic , adverse effect , emergency department , anesthesia , intensive care medicine , analgesic agents , pharmacology , halothane , psychiatry
This article reviews the evidence for the analgesic efficacy of methoxyflurane in both prehospital and ED settings, as well as the adverse event profile associated with methoxyflurane use. Although there are no published controlled trials of methoxyflurane in sub‐anaesthetic doses, available data indicate that it is an efficacious analgesic. There is inadequate evidence regarding its use as an agent for procedural pain. Despite the potential for renal impairment evident when it was used in anaesthetic doses, no significant adverse effects have been reported in the literature, neither in patients nor occupationally, when the dose used is limited to that currently recommended.