Open AccessA favourable response to surgical intervention and hyperbaric oxygen therapy in pyoderma gangrenosum
Author(s) -
Altunay Ilknur,
Kucukunal Asli,
Sarikaya Sezgi,
Tukenmez Demirci Gulsen
Publication year - 2014
Publication title -
international wound journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.867
H-Index - 63
eISSN - 1742-481X
pISSN - 1742-4801
DOI - 10.1111/j.1742-481x.2012.01102.x
Subject(s) - medicine , pyoderma gangrenosum , hyperbaric oxygen , ulcerative colitis , inflammatory bowel disease , monoclonal gammopathy , dermatology , colorectal adenocarcinoma , disease , surgery , neutrophilic dermatosis , colorectal cancer , monoclonal , cancer , monoclonal antibody , immunology , antibody
Pyoderma gangrenosum (PG) is a neutrophilic dermatosis characterised with ulcerations. Inflammatory bowel diseases (ulcerative colitis and Crohn's disease) and haematologic diseases (leukaemia, preleukaemia and monoclonal gammopathy) have been reported in about 40–50% of PG patients in whom the treatment of the underlying disease is important for the improvement of the lesions. We herein report a colorectal adenocarcinoma patient with PG, who responded partially to topical treatments and systemic immunosuppressants and healed completely with the aid of surgical wound repair and hyperbaric oxygen therapy.