Open AccessA multidisciplinary team approach to hydroxyurea‐associated chronic wound with squamous cell carcinoma
Author(s) -
Stone Tamar,
Berger Alexandra,
Blumberg Sheila,
O’Neill Daniel,
Ross Frank,
McMeeking Alexander,
Chen Weiliam,
Pastar Irena
Publication year - 2012
Publication title -
international wound journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.867
H-Index - 63
eISSN - 1742-481X
pISSN - 1742-4801
DOI - 10.1111/j.1742-481x.2011.00887.x
Subject(s) - medicine , basal cell , multidisciplinary team , multidisciplinary approach , chronic wound , oncology , dermatology , wound healing , surgery , nursing , social science , sociology
Hydroxyurea (HU) has been shown to induce a variety of cutaneous adverse reactions, including severe leg ulcers. This report shows a successful treatment of a HU‐induced chronic wound associated with squamous cell carcinomas (SCC). A 62‐year‐old patient affected with polycythemia vera and treated with HU for 10 years, presented with a non healing ulcer on a left heel. The patient gave a history of suffering from the wound for over 2 years. Biopsy showed evidence of invasive SCC. The patient underwent Mohs surgery and a greater saphenous vein ablation for polycythemia vera‐associated vascular complications. The wound consistently decreased in size following successive debridements and coverage with human skin equivalent. The wound healed completely after a 6‐month period. A multidisciplinary team approach to the treatment proved to be effective resulting in healing of this multifactorial chronic ulcer.