Open AccessThe use of recombinant human epidermal growth factor to promote healing for chronic radiation ulcer
Author(s) -
Lee Sangwook,
Moon Sue Young,
Kim Yeun Hwa,
Hong Joon Pio
Publication year - 2007
Publication title -
international wound journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.867
H-Index - 63
eISSN - 1742-481X
pISSN - 1742-4801
DOI - 10.1111/j.1742-481x.2007.00332.x
Subject(s) - medicine , wound healing , recombinant dna , epidermal growth factor , chronic wound , surgery , growth factor , dermatology , gene , biochemistry , chemistry , receptor
This case report describes the first successful use of recombinant human epidermal growth factor (rh‐EGF) in radiation‐induced chronic wound of bone and skin which remains to be difficult to treat. Such wound on the chest of a 59‐year‐old female patient is presented lasting 3 years despite flap surgery and conventional treatment. The treatment with rh‐EGF achieved healing within 16 weeks but further study to evaluate its potential for radiation‐induced chronic wounds is warranted.