Open AccessSegmental ulcerative vasculitis: a cutaneous manifestation of Takayasu's arteritis
Author(s) -
Dourmishev Assen L,
Serafimova Dimitrina K,
Vassileva Snejina G,
Dourmishev Lyubomir A,
Schwartz Robert A
Publication year - 2005
Publication title -
international wound journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.867
H-Index - 63
eISSN - 1742-481X
pISSN - 1742-4801
DOI - 10.1111/j.1742-4801.2005.00103.x
Subject(s) - medicine , arteritis , vasculitis , aortic arch syndrome , trunk , takayasu's arteritis , angiography , disease , radiology , dermatology , pathology , aortic arch , aorta , ecology , biology
A 16‐year‐old girl with pyoderma gangrenosum (PG)‐like skin lesions on the extremities, trunk and face developed Takayasu's arteritis (TA; pulseless disease). After 3 years under maintenance cyclosporin A therapy, the patient developed an ischaemic cerebral accident. Severe obstruction of both subclavian and left carotid arteries was found by Doppler sonography, angiography and computerised axial tomography. Evolution of this disease showed some characteristic findings: (a) PG‐like lesions as the first cutaneous manifestation of pulseless disease; (b) methotrexate and cyclosporin A giving good results for the cutaneous lesions, but apparently not exerting an influence on the evolution of TA and the fatal outcome. This morphologic pattern may reflect underlying TA or Wegener's arteritis, and should be termed segmental ulcerative vasculitis.