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Identification of rice TUBBY‐like genes and their evolution
Author(s) -
Liu Qingpo
Publication year - 2008
Publication title -
the febs journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.981
H-Index - 204
eISSN - 1742-4658
pISSN - 1742-464X
DOI - 10.1111/j.1742-4658.2007.06186.x
Subject(s) - biology , gene , phylogenetic tree , gene duplication , functional divergence , genetics , eukaryote , molecular evolution , multicellular organism , evolutionary biology , phylogenetics , homology (biology) , identification (biology) , gene family , genome , botany
The identification of TUBBY‐like genes in organisms ranging from single‐celled to multicellular eukaryotes has allowed the phylogenetic history of this gene family to be traced back to the early evolutionary stages of eukaryote development. Rice TUBBY‐like genes were located on chromosomes 1, 2, 3, 4, 5, 7, 8, 11 and 12 without any obvious clustering. On a genomic scale, it was revealed that the rice TUBBY‐like gene family probably evolved mainly through segmental duplication produced by polyploidy. The altered selective constraints (or site‐specific rate changes), related to functional divergence during protein evolution between plant and animal TUBBY‐like genes, were statistically significant. Based on posterior probability analysis, five amino acid sites (103, 312, 315, 317 and 319) are thought to be responsible for functional divergence.