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Malaria − an overview
Author(s) -
Tuteja Renu
Publication year - 2007
Publication title -
the febs journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.981
H-Index - 204
eISSN - 1742-4658
pISSN - 1742-464X
DOI - 10.1111/j.1742-4658.2007.05997.x
Subject(s) - malaria , biology , plasmodium (life cycle) , plasmodium falciparum , vector (molecular biology) , parasite hosting , disease , virology , immunology , medicine , genetics , pathology , world wide web , computer science , gene , recombinant dna
Malaria is caused by protozoan parasites of the genus Plasmodium and is a major cause of mortality and morbidity worldwide. These parasites have a complex life cycle in their mosquito vector and vertebrate hosts. The primary factors contributing to the resurgence of malaria are the appearance of drug‐resistant strains of the parasite, the spread of insecticide‐resistant strains of the mosquito and the lack of licensed malaria vaccines of proven efficacy. This minireview includes a summary of the disease, the life cycle of the parasite, information relating to the genome and proteome of the species lethal to humans, Plasmodium falciparum , together with other recent developments in the field.