Open AccessObesity; epiphenomenon or cause of metabolic syndrome?
Author(s) -
Lois K.,
Young J.,
Kumar S.
Publication year - 2008
Publication title -
international journal of clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 98
eISSN - 1742-1241
pISSN - 1368-5031
DOI - 10.1111/j.1742-1241.2008.01773.x
Subject(s) - medicine , metabolic syndrome , abdominal obesity , obesity , insulin resistance , epiphenomenon , disease , type 2 diabetes , diabetes mellitus , endocrinology , bioinformatics , intensive care medicine , philosophy , epistemology , biology
Summary Metabolic syndrome is a combination of metabolic‐related health issues such as hypertension, hyperlipidaemia and hyperinsulinaemia that together increase significantly the risk of cardiovascular disease and type 2 diabetes. Its prevalence has dramatically increased over the last several decades throughout the world following that of obesity. Insulin resistance and abdominal obesity are considered its core, while the latter may generate via complex metabolic and biochemical pathways the rest parameters of metabolic syndrome. The current approach of treatment is based on treating the chronic cardiovascular malfunctions but there is increasing interest in approaches to managing abdominal obesity as the underlying cause.