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Prenatal findings of omphalocele–exstrophy of the bladder–imperforate anus–spinal defects (OEIS) complex
Author(s) -
Goto Shinobu,
Suzumori Nobuhiro,
Obayashi Shintaro,
Mizutani Eita,
Hayashi Yuko,
SugiuraOgasawara Mayumi
Publication year - 2012
Publication title -
congenital anomalies
Language(s) - English
Resource type - Journals
eISSN - 1741-4520
pISSN - 0914-3505
DOI - 10.1111/j.1741-4520.2011.00342.x
Subject(s) - omphalocele , imperforate anus , prenatal diagnosis , cloaca , medicine , spina bifida , cloacal exstrophy , anus , magnetic resonance imaging , anatomy , abdominal wall , bladder exstrophy , radiology , fetus , surgery , pregnancy , biology , genetics
Omphalocele–exstrophy of the bladder (cloaca)–imperforate anus–spinal defects (OEIS) complex describes a rare grouping of more commonly occurring component malformations. We report two cases of OEIS complex diagnosed prenatally by ultrasound and magnetic resonance imaging (MRI). In both cases, OEIS complex was suspected by conventional sonography in the second trimester, and fetal MRI was performed at 27 and 32 weeks of gestation. Conventional sonography revealed low abdominal wall mass, spina bifida, absent bladder and ambiguous genitalia, but those findings were inconclusive. Using fetal MRI, we were able to detect omphalocele, imfraumbilical mass connected to gut tract, absent bladder, ambiguous external genitalia and spinal defect. Our findings suggest that fetal MRI is a useful tool for prenatal diagnosis of OEIS complex. MRI helps prenatal counseling and planning of postnatal early treatment strategy.