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Peters’ anomaly with bilateral perisylvian polymicrogyria and abdominal calcification
Author(s) -
Morimoto Mayumi,
Takano Tomoyuki,
Sakaue Yuko,
Sawai Chihiro,
Aotani Hirofumi,
Koshida Shigeki,
Takeuchi Yoshihiro
Publication year - 2004
Publication title -
congenital anomalies
Language(s) - English
Resource type - Journals
eISSN - 1741-4520
pISSN - 0914-3505
DOI - 10.1111/j.1741-4520.2004.00016.x
Subject(s) - calcification , polymicrogyria , medicine , anatomy , magnetic resonance imaging , pathology , radiology
We report a neonatal case of Peters’ anomaly with bilateral perisylvian polymicrogyria and abdominal calcification. The male infant was born after a normal labor. Bilateral central corneal opacities with iridocorneal strands indicated Peters’ anomaly. The X‐ray and abdominal computed tomography demonstrated multiple calcifications beneath the diaphragma around the liver and the spleen. TORCH serology was negative. Intracranial calcification was not detected. Brain magnetic resonance imaging demonstrated bilateral perisylvian polymicrogyria. Abdominal calcification was suspected to be related to vascular disruption. Bilateral perisylvian polymicrogyria has been thought to result from ischemic events such as intrauterine hypotension or vascular occlusions. Based on these considerations, we conclude that a vascular disruption sequence may an important pathogenetic mechanism of Peters’ anomaly.