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Application of the mouse exo utero development system in the study of developmental biology and teratology
Author(s) -
Hatta Toshihisa,
Matsumoto Akihiro,
Otani Hiroki
Publication year - 2004
Publication title -
congenital anomalies
Language(s) - English
Resource type - Journals
eISSN - 1741-4520
pISSN - 0914-3505
DOI - 10.1111/j.1741-4520.2003.00002.x
Subject(s) - teratology , histogenesis , in utero , developmental biology , biology , developmental science , laboratory mouse , embryo , fetus , physiology , pregnancy , neuroscience , genetics , immunology , immunohistochemistry , gene
The mouse exo utero development system is useful for analyzing the roles of molecules or interactions between tissues in the histogenesis of organs after the mid‐gestational period. In the article presented here, we review the mouse exo utero development system and its specific modifications depending on different purposes as well as its advantages over and limitations compared to other systems in the study of developmental biology and teratology.