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A Sterile 21, X Chinese Hamster
Author(s) -
SONTA Shinichi,
SEMBA Reiji
Publication year - 1987
Publication title -
congenital anomalies
Language(s) - English
Resource type - Journals
eISSN - 1741-4520
pISSN - 0914-3505
DOI - 10.1111/j.1741-4520.1987.tb00706.x
Subject(s) - chinese hamster , hamster , estrous cycle , biology , golden hamster , follicle , oocyte , andrology , karyotype , chromosomal translocation , anatomy , chromosome , embryo , genetics , endocrinology , medicine , cell culture , gene
A Chinese hamster with a single X chromosome was found in 23 off‐spring from crosses between a male heterozygous for T(1;3)8Idr translocation and karyologically normal females. All karyotypes of cells from various tissues of this animal were 21, X. The animal had an external genitalia generally characteristic to the female but no typical proestrous and estrous figure was found in the vaginal smear, and the animal showed no indication of pregnancy by any crosses. On autopsy, two gonads were found. Microscopically, there were some large fluid‐filled cysts and many follicle‐like bodies in the cortex of both gonads, but no mature follicle containing an oocyte was observed. The XO conditions in the Chinese hamster are compared with those of other mammals.