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Comparison of Fatigue Resistant Properties of Gastrocnemius and Soleus Muscles between Muscular Dystrophic Mice and Other Strains of Mice
Author(s) -
TOTSUKA Tsuyoshi,
WATANABE Kimi,
URAMOTO Isao,
KIYONO Sigehiro
Publication year - 1984
Publication title -
congenital anomalies
Language(s) - English
Resource type - Journals
eISSN - 1741-4520
pISSN - 0914-3505
DOI - 10.1111/j.1741-4520.1984.tb00368.x
Subject(s) - strain (injury) , muscular dystrophy , sciatic nerve , stimulation , gastrocnemius muscle , chemistry , anatomy , endocrinology , soleus muscle , medicine , biology , skeletal muscle
Muscular potentials were recorded from medial gastrocnemius (MG) and soleus muscles (SOL) of dystrophic and normal mice of the strain C57BL/6J‐ dy , dwarf and normal mice of the strain DW/J, and brachymorphic mice of the strain C57BL/6J‐Zwi. The mice were anesthetized with urethane and the sciatic nerve was stimulated at 0.5 and 5 Hz with square pulses. When the frequency of stimulation was raised from 0.5 to 5 Hz and maintained at the latter frequency for 10 min, muscular potentials of dystrophic MG decreased slightly, whereas the other MGs showed a rapid and remarkable reduction in amplitudes. In addition, muscular potentials of SOL of all mice were slightly potentiated. Thus, changing patterns of muscular potentials of dystrophic MG were shifted toward those characteristic of SOLs.