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Hematological and Immunological Changes with Age
Author(s) -
Wolf Norman S.
Publication year - 1984
Publication title -
gerodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 54
eISSN - 1741-2358
pISSN - 0734-0664
DOI - 10.1111/j.1741-2358.1984.tb00350.x
Subject(s) - medicine , myeloid cells , immune system , stem cell , myeloid , homeostasis , immunology , microbiology and biotechnology , biology
The development of both myeloid cells and immunocytes from a common stem cell precursor, their differentiated pathways, functions and the factors which modulate them are briefly reviewed here. The age‐related decline (or lack of it) for the several cell lines is outlined, as well as the effect of this upon life processes and homeostasis. The results from two approaches to extending high levels of immune responses in aged mice are reviewed.