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CT‐GUIDED STEREOTACTIC BRAIN BIOPSY USING THE KOPF STEREOTACTIC SYSTEM
Author(s) -
TROXEL MARK T.,
VITE CHARLES H.
Publication year - 2008
Publication title -
veterinary radiology and ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.541
H-Index - 60
eISSN - 1740-8261
pISSN - 1058-8183
DOI - 10.1111/j.1740-8261.2008.00403.x
Subject(s) - medicine , stereotactic biopsy , biopsy , cadaver , radiology , stereotactic surgery , brain biopsy , computed tomographic , nuclear medicine , computed tomography , surgery
This report describes computed tomography (CT)‐guided stereotactic brain biopsy using the Kopf stereotactic system, a commercially available patient restraint system which does not require additional modification for use in small animals. The accuracy of biopsy needle placement was determined by injecting dilute iohexol into cadaver brains and comparing the three‐dimensional coordinates of the desired target location to the actual needle tract observed on postcontrast CT images. Overall mean error in needle placement in a dorsoventral trajectory was 0.9±0.9 mm ( n =80 injections) for dogs and 1.0±1.1 mm ( n =30 injections) for cats. The overall mean error in needle placement via an oblique trajectory in five dogs was 1.7±1.6 mm ( n =12 injections). These results suggest that this system can be used to successfully place a biopsy needle into the brain to obtain biopsies from small lesions.

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