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EVALUATION OF A NOVEL DOPPLER INDEX OF COMBINED SYSTOLIC AND DIASTOLIC MYOCARDIAL PERFORMANCE IN NEWFOUNDLAND DOGS WITH FAMILIAL PREVALENCE OF DILATED CARDIOMYOPATHY
Author(s) -
Lee ByeongHan,
DukesMcEwan Joanna,
French Anne T.,
Corcoran Brendan M.
Publication year - 2002
Publication title -
veterinary radiology and ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.541
H-Index - 60
eISSN - 1740-8261
pISSN - 1058-8183
DOI - 10.1111/j.1740-8261.2002.tb01663.x
Subject(s) - medicine , cardiology , dilated cardiomyopathy , isovolumic relaxation time , diastole , doppler echocardiography , cardiomyopathy , isovolumetric contraction , occult , ejection fraction , heart failure , blood pressure , pathology , alternative medicine
A Doppler index of myocardial performance (IMP) has been recently proposed in human cardiology, which is calculated from the isovolumic contraction time (ICT), isovolumic relaxation time (IRT), and the ejection time (ET) using the following formula: (ICT+IRT)/ET. In this study, IMP was measured and evaluated in Newfoundland dogs categorized in four groups: Normal dogs (n = 31), dilated cardiomyopathy (DCM) (n = 34), depressed fractional shortening (dFS) (n = 27), and left ventricular enlargement (LVE) (n = 7). IMP was found to be independent of age, sex, body surface area, and the R‐R interval in the Normal group. There were significant differences in IMP between the DCM group and the Normal and dFS groups ( P < 0.05) and between Newfoundlands with overt vs. occult DCM. IMP is a Doppler index which appears to correlate with severity of disease and may be of use in the early diagnosis of affected dogs during screening for the presence of DCM.