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QUANTITATIVE EVALUATION OF IMAGENT® AS AN ABDOMINAL ULTRASOUND CONTRAST MEDIUM IN DOGS
Author(s) -
Bahr Anne,
Wrigley Robert,
Salman Mowafak
Publication year - 2000
Publication title -
veterinary radiology and ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.541
H-Index - 60
eISSN - 1740-8261
pISSN - 1058-8183
DOI - 10.1111/j.1740-8261.2000.tb00427.x
Subject(s) - medicine , ultrasound , radiology , contrast (vision) , contrast medium , contrast enhanced ultrasound , nuclear medicine , medical physics , computer vision , computer science
Diagnostic ultrasound currently provides a noninvasive, economical means to evaluate internal organ structure. Methods to increase the amount of diagnostic information obtained from the sonographic examination are being explored. A new area of research has recently focused on the ability of mi‐crobubble contrast agents to help provide additional information. A prospective study was undertaken to quantitatively evaluate the amount of gray scale enhancement of ultrasound images of six canine livers, spleens, and left kidneys that occurs after intravenous injection of Imagent.® Computerized analysis was used to assess the percent change in brightness of these images. A transient decrease in the percent change in brightness was seen to occur after injection of higher doses of Imagent.® This effect was more pronounced in the deeper portions of the organs of interest. Imagent® provides a measurable change in the brightness of the organs of interest and would be potentially useful in a clinical setting.