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EVALUATION OF RENAL HEMODYNAMICS IN AWAKE AND ISOFLURANE‐ANESTHETIZED CATS WITH PULSED‐WAVE DOPPLER AND QUANTITATIVE RENAL SCINTIGRAPHY
Author(s) -
Mitchell Sally K.,
Toal Robert L.,
Daniel Gregory B.,
Rohrbach Barton W.
Publication year - 1998
Publication title -
veterinary radiology and ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.541
H-Index - 60
eISSN - 1740-8261
pISSN - 1058-8183
DOI - 10.1111/j.1740-8261.1998.tb01634.x
Subject(s) - medicine , isoflurane , hemodynamics , doppler effect , cats , anesthesia , scintigraphy , cardiology , physics , astronomy
The feasibility and reproducibility of obtaining the pulsed‐wave Doppler measurements of resistive index (RI) and pulsatility index (PI) were investigated in intrarenal arteries of normal, nonsedated cats, and cats anesthetized with isoflurane. In addition, relative renal function and relative renal blood flow were evaluated using quantitative renal scintigraphy. The percentage of injected dose uptake, time to peak activity, and two indices of renal blood flow (K/A ratio and flow index) obtained during the first pass of 99m Tc‐MAG 3 , were determined for both awake and anesthetized cats. Results indicate that measuring RI and PI in nonsedated cats is readily accomplished and that the results are reproducible within an animal. Mean RI and PI values in the awake cats were 0.55 and 0.8, respectively. Significant differences between the awake and anesthetized cats were found for all pulsed‐wave Doppler and quantitative renal scintigraphic measurements evaluated.