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COMPUTED TOMOGRAPHY OF RAMBOUILLET SHEEP AFFECTED WITH NEURONAL CEROID LIPOFUSCINOSIS
Author(s) -
Woods Philip R.,
Walker Michael A.,
Weir Vicki A.,
Storts Ralph W.,
Menzies Carl,
Shelton Maurice
Publication year - 1993
Publication title -
veterinary radiology and ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.541
H-Index - 60
eISSN - 1740-8261
pISSN - 1058-8183
DOI - 10.1111/j.1740-8261.1993.tb01574.x
Subject(s) - neuronal ceroid lipofuscinosis , medicine , computed tomography , pathology , lipofuscin , anatomy , radiology , disease
Computed tomography (CT) was performed on 3 normal Rambouillet sheep and 6 Rambouillet sheep affected with neuronal ceroid lipofuscinosis. Characteristic lesions seen in the brain of affected sheep included dramatically enlarged lateral ventricles and reduced cerebral thickness. The lesions were seen in sheep as young as 4 months of age. Antemortem CT observations correlated well with postmortem findings in this model of Neuronal Ceroid Lipofuscinosis.