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OSTEOGENIC SARCOMA OF THE NASAL CAVITY IN A CAT: POSTOPERATIVE CONTROL WITH HIGH DOSE‐PER‐FRACTION RADIATION THERAPY AND METRONIDAZOLE
Author(s) -
Lord Peter F.,
Kapp Daniel S.,
Schwartz Anthony,
Morrow David T.
Publication year - 1982
Publication title -
veterinary radiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.541
H-Index - 60
eISSN - 1740-8261
pISSN - 0196-3627
DOI - 10.1111/j.1740-8261.1982.tb00704.x
Subject(s) - metronidazole , medicine , nasal cavity , sarcoma , radiation therapy , oral cavity , surgery , nuclear medicine , dentistry , antibiotics , pathology , biology , microbiology and biotechnology
An 11‐year‐old Siamese cat with an osteogenic sarcoma of the nasal cavity was treated by partial surgical excision followed by a course of high dose‐per‐fraction radiation therapy in conjuction with metronidazole, a hypoxic cell sensitizer. Four thousand two hundred rads were delivered to the tumor in 7 weekly fractions. Each treatment was preceded by 6 gm/m 2 oral metronidazole given 3 hours before irradiation. There were no untoward side effects and the cat was in remission 2 years after treatment.