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Effect of a Nano‐Hydroxyapatite Paste on Bleaching‐Related Tooth Sensitivity
Author(s) -
BROWNING WILLIAM D.,
CHO SOPANIS D.,
DESCHEPPER EDWARD J.
Publication year - 2012
Publication title -
journal of esthetic and restorative dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.919
H-Index - 60
eISSN - 1708-8240
pISSN - 1496-4155
DOI - 10.1111/j.1708-8240.2011.00437.x
Subject(s) - tooth sensitivity , carbamide peroxide , dentistry , visual analogue scale , medicine , enamel paint , hydrogen peroxide , placebo , randomized controlled trial , tooth whitening , chemistry , surgery , alternative medicine , organic chemistry , pathology
Statement of the Problem: Bleaching‐related tooth sensitivity has been shown to be facilitated by the presence of enamel defects. A nano‐hydroxyapatite (n‐HAP) paste has been shown to repair these defects. Purpose of the Study: Using a randomized clinical trial, an n‐HAP paste was investigated to determine its efficacy in reducing bleaching‐related tooth sensitivity. Methods and Materials: An n‐HAP paste (Renamel AfterBleach®, Sangi Co., Ltd., Tokyo, Japan) and a placebo (zero‐HAP) were randomly assigned for use in 42 participants. A 7% hydrogen peroxide gel was used twice daily for 14 days, with use of assigned desensitizer for 5 minutes immediately following. A diary was completed daily for 4 weeks to note: use of the agents and sensitivity on a visual analog scale (VAS). Three aspects of tooth sensitivity were investigated: percentage of participants; number of days; and intensity level. Color change was assessed. Results: For Groups zero‐HAP and n‐HAP, respectively, 51 and 29% of participants reported tooth sensitivity ( p = 0.06). Days of sensitivity were 76 and 36, respectively ( p = 0.001). Change in VAS score from baseline trended higher for Group zero‐HAP ( p = 0.16). Color change was equivalent. Discussion: The data trend indicated Group n‐HAP experienced less sensitivity over all three measures. Only the number of days of sensitivity was statistically significant. Conclusion: Within the limits of the study it can be concluded that the use of the n‐HAP paste was associated with a statistically significant reduction in the number of days of tooth sensitivity experienced during active bleaching. CLINICAL RELEVANCE For those using a tooth whitener without a desensitizing agent, this study indicates that a paste containing nano‐hydroxyapatite crystal can effectively reduce the duration of tooth sensitivity. (J Esthet Restor Dent 24:268–276, 2012)