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Maxillary Sinus Augmentation in Humans Using Cortical Porcine Bone: A Histological and Histomorphometrical Evaluation After 4 and 6 Months
Author(s) -
Scarano Antonio,
Piattelli Adriano,
Perrotti Vittoria,
Manzon Licia,
Iezzi Giovanna
Publication year - 2011
Publication title -
clinical implant dentistry and related research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.338
H-Index - 85
eISSN - 1708-8208
pISSN - 1523-0899
DOI - 10.1111/j.1708-8208.2009.00176.x
Subject(s) - maxillary sinus , biocompatible material , cortical bone , medicine , osteocyte , sinus (botany) , bone marrow , dentistry , biomaterial , pathology , biomedical engineering , chemistry , biology , osteoblast , biochemistry , botany , in vitro , genus
Background: Bone substitutes, such as allografts, xenografts, and alloplasts, have been proposed in several augmentation procedures. Purpose: The aim of the present study was a histologic and histomorphometric evaluation of specimens retrieved 4 or 6 months after sinus augmentation using cortical porcine bone augmentation material. Materials and Methods: A total of 77 specimens, retrieved after 4 and 6 months from augmented sinuses, were used in this study. The specimens were processed to be observed under light microscopy. Histomorphometric measurements were presented as means ± standard deviations. Results: Most of the particles were surrounded by newly formed bone with large osteocyte lacunae. Histomorphometry showed that, after 4 months, the newly formed bone represented 28%, marrow spaces 36%, the residual graft material 37%, while, after 6 months, the newly formed bone represented 31%, marrow spaces 34%, while the residual graft material was 37%. Conclusion: The present results show that cortical porcine bone is a biocompatible, osteoconductive biomaterial that can be used for maxillary sinus augmentation procedures without interfering with the normal reparative bone processes.