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Proximal‐type epithelioid sarcoma in the pelvic soft tissues
Author(s) -
FUKUNAGA MASAHARU,
USHIGOME SHINICHIRO
Publication year - 1999
Publication title -
apmis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0903-4641
DOI - 10.1111/j.1699-0463.1999.tb01555.x
Subject(s) - epithelioid sarcoma , pathology , cytokeratin , vimentin , cd34 , hyaline , epithelioid cell , differential diagnosis , sarcoma , biology , eosinophilic , lymph node , soft tissue , medicine , immunohistochemistry , stem cell , genetics
A case of proximal‐type epithelioid sarcoma arising in the pelvic soft tissues of a 46‐year‐old man is presented. The tumor showed a predominantly epithelioid component with rhabdoid features, cordlike arrangement, small nests, abundant eosinophilic cytoplasm containing intracytoplasmic, paranuclear, hyaline‐like globules, large vesicular nuclei, and prominent nucleoli. There were foci with alveolar arrangement and a spindle‐cell proliferation. The tumor cells were positive for cytokeratin CAM5.2, vimentin, epithelial membrane antigen, and CD34. Flow cytometry showed a diploid DNA content with high S‐phase fraction. The patient had pelvic lymph‐node metastases. He died of the disease 5 months after diagnosis. It is important to include proximal‐type epithelioid sarcoma in the differential diagnosis of pelvic tumors.