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Early stages in male germ cell differentiation in the mouse
Author(s) -
ANDERSON ROBERT,
GARCIACASTRO MARTIN,
HEASMAN JANET,
WYLIE CHRISTOPHER
Publication year - 1998
Publication title -
apmis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0903-4641
DOI - 10.1111/j.1699-0463.1998.tb01327.x
Subject(s) - primordium , organogenesis , gastrulation , germ line development , gonad , biology , germ cell , germ plasm , microbiology and biotechnology , embryo , germ , hindgut , germ layer , embryogenesis , anatomy , embryonic stem cell , genetics , larva , gene , botany , midgut , induced pluripotent stem cell
Primordial germ cells arise during gastrulation and migrate from the hindgut into the gonad primordium during early organogenesis. In this article, we discuss factors that control migration, proliferation and targeting of the PGCs. In particular we discuss how changes in adhesiveness control germ cell positioning in the gonad, and the molecules involved.