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Interstitial cystitis
Author(s) -
HORN THOMAS,
HOLM NINA RAAE,
HALD TAGE
Publication year - 1998
Publication title -
apmis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0903-4641
DOI - 10.1111/j.1699-0463.1998.tb00238.x
Subject(s) - ultrastructure , sarcolemma , interstitial cystitis , detrusor muscle , pathology , smooth muscle , chemistry , anatomy , medicine , myocyte , biology , microbiology and biotechnology , alternative medicine
Ultrastructural investigation of detrusor muscle cells in biopsies from 13 patients (8 interstitial cystitis (IC) and 5 controls) was performed. In all IC‐patients and in one control a varying number of smooth muscle cells revealed a characteristic oak leaf pattern with protrusions of the sarcolemma. The alterations may express degeneration of smooth muscle cells. Although most probably non‐specific yet highly characteristic, the ultrastructural detrusor changes may be important in diagnosing IC.