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Imprint cytology of cat scratch disease
Author(s) -
KOJIMA MASARU,
NAKAMURA SHIGEO,
KOSHIKAWA TAKASHI,
KURABAYASHI YOSHIYUKI,
SENPUKU AKIKO,
YAMANE NOBUO,
ITOH HIDEAKI,
YOSHIDA KATSUE,
HOSOMURA YASUO,
SUCHI TAIZAN,
JOSHITA TAKASHI
Publication year - 1996
Publication title -
apmis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0903-4641
DOI - 10.1111/j.1699-0463.1996.tb00732.x
Subject(s) - cat scratch disease , epithelioid cell , histopathology , pathology , cytology , lymph node , stain , medicine , bartonella henselae , biology , staining , disease , immunohistochemistry , immunology , antibody , serology
The cytologic features of cat scratch disease (CSD) from eight cases in imprint smears are presented. All patients were clinicopathologically diagnosed as CSD as follows: 1) a history of animal exposure was recorded 2 to 4 weeks before lymphadenopathy; 2) the disease occurred in the autumn and winter months; 3) a characteristic histopathology in the biopsied lymph node specimens was observed; and 4) Warthin‐Starry silver stain‐positive bacteria were detected in four of the seven cases examined. The characteristic cytologic finding was the presence of confluent epithelioid cells with nearby and central scatterjng of neutrophils against a background of polymorphic inflammatory cells. Furthermore, a varying number of medium‐sized to large lymphoid cells with an appearance suggestive of monocytoid B lymphocytes (MBLs) were noted to be associated with the epithelioid cells. These cytologic findings closely paralleled the histologic patterns of epithelioid cell granulomas, with and without MBLs, which we have previously reported are probably associated with the disease.