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Antibodies to Helicobacter pylori in dyspeptic patients, asymptomatic adults, and children from Costa Rica
Author(s) -
Bartels GISELLE,
Herrera ADELITA,
Salas PILAR,
Sierra RAFAELA,
Lomonte BRUNO
Publication year - 1995
Publication title -
apmis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0903-4641
DOI - 10.1111/j.1699-0463.1995.tb01128.x
Subject(s) - seroprevalence , asymptomatic , helicobacter pylori , antibody , medicine , incidence (geometry) , gastroenterology , immunoassay , immunology , serology , physics , optics
An enzyme immunoassay for the detection of serum IgG antibodies to H. pylori whole bacterial sonicate was used in a study of dyspeptic adult patients (n=165), apparently healthy blood donors (n=154), and children (n = 66) from Costa Rica, where a very high incidence of gastric carcinoma is observed. The mean antibody levels and frequency distributions were similar in the dyspeptic patients and the blood donors. Meanwhile lower antibody levels to H. pylori were more frequently observed in children than in adults, suggesting an age‐dependent increase in seroprevalence, as described in studies from other populations.