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A case of Whipple's disease presenting as supraclavicular lymphadenopathy
Author(s) -
EREÑO COSME,
LOPEZ JOSE I.,
ELIZALDE JESUS M.,
IBANEZ TERESA,
FDEZLARRINOA AITOR,
TOLEDO JUAN D.
Publication year - 1993
Publication title -
apmis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0903-4641
DOI - 10.1111/j.1699-0463.1993.tb00193.x
Subject(s) - medicine , differential diagnosis , cervical lymphadenopathy , presentation (obstetrics) , whipple's disease , lymphatic disease , biopsy , lymph node biopsy , whipple disease , lymph node , disease , surgery , pathology , coeliac disease , intestinal malabsorption
A case of Whipple's disease occurring in a 63‐year‐old woman is reported. Cervical lymphadenopathy and vague constitutional symptoms were soon followed by diarrhea and weight loss. Supraclavicular lymph node exeresis suggested the initial diagnosis, which was confirmed by intestinal biopsy. The concurrence of cystic spaces, PAS‐positive foamy histiocytes and epithelioid granulomas is considered by the authors to provide a useful histological clue in the diagnosis of lymph node involvement in Whipple's disease. Pathologists must be aware of such an un‐conventional presentation of this rare entity and therefore include it within the differential diagnosis of cervical and/or axillary lymphadenopathies.