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Correlations of peritoneal interleukin‐6, serum beta‐2 microglobulin and urinary beta‐2 microglobulin after elective abdominal surgery
Author(s) -
TSUKADA KATSUHIKO,
KATOH HIROYUKI,
SUZUKI TANJI,
TAKENOSHITA SEIICHI,
NAGAMACHI YUKIO
Publication year - 1993
Publication title -
apmis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0903-4641
DOI - 10.1111/j.1699-0463.1993.tb00128.x
Subject(s) - beta 2 microglobulin , medicine , urinary system , beta (programming language) , urology , abdominal surgery , gastroenterology , surgery , computer science , programming language
Postoperative peritoneal interleukin‐6 (P‐IL‐6), serum beta‐2 microglobulin (SBMG) and urinary beta‐2 microglobulin (UBMG) concentrations were examined in 33 patients who underwent various types of abdominal surgery. Similar time‐dependent changes in SBMG and UBMG were observed in five other patients who underwent abdominal surgery. SBMG decreased the first day after the operation (1POD), then increased and reached the preoperative level by the third day after the operation (3POD). UBMG started to increase 1POD, reached the maximum 3POD, then decreased. The 1POD SBMG concentration was significantly correlated with P‐IL‐6, and 3POD UBMG was also significantly correlated with P‐IL‐6. These findings indicate that serum and urinary beta‐2 microglobulin concentrations are closely correlated with P‐IL‐6.