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β‐lactamases in Shigella
Author(s) -
SCHUMACHER H.,
NIR M.,
MANSA B.,
GRASSY A.
Publication year - 1992
Publication title -
apmis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0903-4641
DOI - 10.1111/j.1699-0463.1992.tb04024.x
Subject(s) - shigella flexneri , mecillinam , microbiology and biotechnology , cefotaxime , shigella , ampicillin , shigella sonnei , amp resistance , ciprofloxacin , escherichia coli , biology , antibiotics , enterobacteriaceae , genetics , gene
The occurrence of resistance and production of β‐lactamases was investigated in 60 Shigella strains. Ampicillin resistance was found in 28 (47%) of the isolates, the resistance being more frequent in Sh. flexneri than in Sh. sonnei. All strains were susceptible to cefotaxime, mecillinam, and ciprofloxacin. The β‐lactamases produced by Shigella were similar to TEM‐1, OXA‐1, or the low‐level chromosomally mediated cephalosporinase produced by Escherichia coli. The β‐lactamases produced by Sh. flexneri were most often the OXA‐1‐like enzymes.