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Bacteriological autopsy II. Comparison of a group of cancer patients with a control group
Author(s) -
LARSEN KNUD ERIK,
SØGAARD PER,
BUHL LINE,
LOU HANNE ELISABETH,
HENRIQUES ULRIK
Publication year - 1991
Publication title -
apmis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0903-4641
DOI - 10.1111/j.1699-0463.1991.tb05189.x
Subject(s) - autopsy , medicine , cancer , grading (engineering) , pathology , disease , inflammation , microbiological culture , gastroenterology , bacteria , biology , ecology , genetics
A study of the results of bacteriological autopsy in a group of cancer patients compared with a control group was carried out. Autopsy was performed on 42 bodies within 24 hours of death. Thirty‐two patients had died with a cancer and the remaining ten had died of cardiovascular disease. Tissue for microscopy and material and culture were taken from the same sites. The results of the inoculations were semiquantified, resulting in a culture score, and the results of the microscopy were classified according to presence of bacteria and kind of inflammation. Furthermore, grading was done according to the degree of inflammation and whether bacteria were seen at microscopy. The culture scores were significantly higher in the cancer group than in the control group. We found a significant correlation between score and presence of acute inflammation. Likewise, a significant correlation was found between score and presence of bacteria at microscopy. As a difference between the cancer group and the control group was seen, further research on bacteriological autopsy seems worthwhile.