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Increased oxygen radical production determined by whole blood chemiluminescence in patients with previous yersinia arthritis
Author(s) -
Ristola MATTI
Publication year - 1990
Publication title -
apmis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0903-4641
DOI - 10.1111/j.1699-0463.1990.tb01011.x
Subject(s) - chemiluminescence , zymosan , luminol , yersinia infections , yersinia , medicine , arthritis , opsonin , immunology , whole blood , chemistry , rheumatoid arthritis , endocrinology , phagocytosis , biology , biochemistry , bacteria , enterobacteriaceae , escherichia coli , chromatography , genetics , in vitro , gene
Luminol‐dependent whole blood chemiluminescence (CL) was studied in patients with previous yersinia arthritis (YA). Patients showed significantly higher CL responses compared to healthy controls regardless of HLA‐B27 antigen when either N‐formyl‐methionyl‐leucyl‐phenylalanine or opsonized zymosan particles were used a stimulus. This hyperreactivity may well play a role in the development of inflammatory injury in YA.