Premium
Bacterial adherence to endothelial cells from rat heart, with special regard to alpha‐hemolytic streptococci
Author(s) -
SCHOLLIN JENS,
DANIELSSON DAN
Publication year - 1988
Publication title -
apmis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0903-4641
DOI - 10.1111/j.1699-0463.1988.tb05326.x
Subject(s) - microbiology and biotechnology , neisseria meningitidis , in vitro , neisseria gonorrhoeae , streptococcus , group a , infective endocarditis , antigen , biology , staphylococcus aureus , medicine , bacteria , immunology , biochemistry , genetics
Endothelial cells were prepared from rat heart, and the ability of various bacterial species to adhere to these cells was investigated, with special regard to alpha‐hemolytic streptococci. The endothelial cells were identified by morphology and by the presence of F VIII antigen. Seventeen bacterial strains representing various species were used in the in vitro adherence tests; 10 strains represented various strains of alpha‐hemolytic streptococci, 5 of which were isolated from patients with infective endocarditis and 5 from the throats of healthy individuals; 2 were Neisseria meningitidis, 2 N. gonorrhoeae, 2 S. aureus and 1 E. coli. The highest adherence rate was found for alpha‐hemolytic streptococci isolated from patients with infective endocarditis. The difference compared to carrier strains of alpha‐hemolytic streptococci and to the other tested strains was statistically highly significant.