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IN VITRO SUSCEPTIBILITY OF CAMPYLOBACTER JEJUNI AND CAMPYLOBACTER COLI ISOLATED IN DENMARK TO FOURTEEN ANTIMICROBIAL AGENTS
Author(s) -
Andreasen JAN JESPER
Publication year - 1987
Publication title -
acta pathologica microbiologica scandinavica series b: microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0180
DOI - 10.1111/j.1699-0463.1987.tb03110.x
Subject(s) - erythromycin , campylobacter jejuni , clindamycin , ciprofloxacin , campylobacter , microbiology and biotechnology , antimicrobial , gentamicin , agar dilution , campylobacter coli , antibiotics , doxycycline , biology , minimum inhibitory concentration , bacteria , genetics
The in vitro susceptibility of 95 recent Danish human clinical isolates of Campylobacter jejuni and Campylobacter coli to 14 antimicrobial agents was determined by an agar dilution technique. C. jejuni and C. coli were considered together. Doxycycline, ciprofloxacin, gentamicin, clindamycin, nitrofurantoin and erythromycin were the most active drugs. 2% of the strains tested were resistant to erythromycin (MIC > 3.1 μg/ml). Therefore susceptibility testing is suggested if antimicrobial therapy with erythromycin is considered to be indicated. Ciprofloxacin might prove to be an alternative to erythromycin. Susceptibility testing in a CO 2 atmosphere affected the determination of MICs of doxycycline, erythromycin, gentamicin and clindamycin, probably reflecting pH‐changes in the media during incubation under increased CO 2 tension.