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GENETIC HETEROGENEITY OF FLAVOBACTERIUM MENINGOSEPTICUM DEMONSTRATED BY DNA‐DNA HYBRIDIZATION
Author(s) -
Ursing JAN,
Bruun BRITA
Publication year - 1987
Publication title -
acta pathologica microbiologica scandinavica series b: microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0180
DOI - 10.1111/j.1699-0463.1987.tb03084.x
Subject(s) - flavobacterium , dna , dna–dna hybridization , biology , genetics , bacteria , pseudomonas
DNA‐DNA reassociation studies on 52 strains of Flavobacterium meningosepticum showed two main hybridization groups about 40–55% interrelated and comprising 4 and 48 strains respectively. The larger group could be further divided into four subgroups if differences in thermal stability of the reassociated duplexes were taken into consideration. Of a total of 20 strains isolated from cerebrospinal fluid, 18 were found in one subgroup of 28 strains, which also contained seven blood isolates. The results indicate that genetically defined subgroups within the species might differ with regard to pathogenic significance.