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THE MUMPS‐SPECIFIC T CELL RESPONSE IN HEALTHY INDIVIDUALS AND INSULIN‐DEPENDENT DIABETICS: PREFERENTIAL RESTRICTION BY DR4‐ASSOCIATED ELEMENTS
Author(s) -
Bruserud øYstein,
Paulsen Gunnar,
Thorsby Erik
Publication year - 1987
Publication title -
acta pathologica microbiologica scandinavica series c: immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0202
DOI - 10.1111/j.1699-0463.1987.tb00027.x
Subject(s) - heterozygote advantage , biology , genetics , genotype , gene
An increased frequency of mumps‐specific T lymphocytes restricted by DR4‐associated elements has previously been described in DR4 heterozygotes. Here we report that the preferential restriction elements may be present on DR4 molecules expressing either Dw4 or Dw14. No particular genomic DQ‐β polymorphism was associated with the preferential restriction elements.