Premium
IMMUNOGLOBULINS AND INNATE FACTORS OF IMMUNITY IN SALIVA OF CHILDREN PRONE TO RESPIRATORY INFECTIONS
Author(s) -
Lehtonen O.P. J.,
Tenovuo J.,
Aaltonen A. S.,
Vilja P.
Publication year - 1987
Publication title -
acta pathologica microbiologica scandinavica series c: immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0202
DOI - 10.1111/j.1699-0463.1987.tb00006.x
Subject(s) - lactoferrin , saliva , immunology , immunoglobulin a , antibody , innate immune system , respiratory system , immunity , lysozyme , immunoglobulin e , medicine , immune system , immunoglobulin g , biology , genetics
Serum and salivary total IgA, IgG and IgM as well as salivary innate non‐immunoglobulin antimicrobial factors (lysozyme, lactoferrin, salivary and leukocyte peroxidase systems) were measured in 13 children prone to recurrent respiratory infections and compared to their age‐matched healthy controls. Serum IgG and IgM levels were significantly elevated and salivary IgA remarkably low in infection‐prone children as compared to the controls. However, the levels of secretory piece‐bearing IgA were about the same in both groups. There were no significant differences between the two groups in serum IgA levels or in any of the non‐immunoglobulin factors. The results indicate that low salivary IgA is associated with recurrent respiratory infections.