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TUMOURS IN ICELAND 8. Hodgkin's Disease and non‐Hodgkin's Malignant Lymphomas. A histological Classification and Epidemiological Considerations
Author(s) -
AGNARSSON BJARNI A.,
ÓLAFSDÓTTIR KRISTRÚN,
BENEDIKTSSON HALLGRÍMUR
Publication year - 1987
Publication title -
acta pathologica microbiologica scandinavica series a :pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0164
DOI - 10.1111/j.1699-0463.1987.tb00005_95a.x
Subject(s) - nodular sclerosis , incidence (geometry) , lymphoma , disease , epidemiology , medicine , hodgkin lymphoma , working formulation , male to female , pathology , biopsy , non hodgkin's lymphoma , physics , optics
All cases of biopsy‐proven Hodgkin's disease and non‐Hodgkin's lymphomas submitted for histological diagnosis in Iceland during 1955–1982 and available for review were typed histologically, using the World Health Organization Classification for cases of Hodgkin's disease and the “International Working Formulation” for cases of non‐Hodgkin's lymphoma. A total of 92 cases of Hodgkin's disease were classified with a male‐to‐female ratio of 1.96. The largest subgroups were those of nodular sclerosis (42%) and mixed cellularity (32%). A prominent peak in the incidence was found in the 21–30 years age group. The incidence and subtypes of Hodgkin's disease in Iceland appears similar to those found in other Western countries. A total of 90 cases of non‐Hodgkin's lymphomas were classified with a male‐to‐female ratio of 1.5. A high incidence of large cell lymphomas was found, especially of the immunoblastic type (35%), while in other respects the distribution of subtypes appeared similar to what has been found in studies from other Western countries. The incidence of non‐Hodgkin's lymphomas in Iceland is low during childhood and young adulthood but rises sharply after age 50 and the overall incidence is similar to that found in other European countries.