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REPEATED PASSAGE OF FRESHLY ISOLATED GROUP A STREPTOCOCCI ON BLOOD AGAR
Author(s) -
StjernquistDesatnik ANNA,
Kurl DAYA N.,
Christensen POUL
Publication year - 1986
Publication title -
acta pathologica microbiologica scandinavica series b: microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0180
DOI - 10.1111/j.1699-0463.1986.tb03075.x
Subject(s) - microbiology and biotechnology , agar , group a , agar plate , asymptomatic carrier , group b , buccal swab , strain (injury) , biology , asymptomatic , throat , bacteria , medicine , pathology , anatomy , genetics
Group A streptococcal strains (three T‐type 1, two T‐type 2 and three T‐type 4), freshly isolated from throat cultures, were subjected to 25 serial passages on blood agar. All strains changed their M protein production and/or opacity factor (OF)‐activity during the passages. The capacity of each strain to adhere to a pool of buccal cells from six healthy individuals was studied both before and after passage. Five of six strains with decreased OF‐activity/M protein production diminished significantly in adherence capacity, whereas one of two strains with increasing OF‐activity adhered better to the epithelial cells. The results are discussed in relation to the clinical view of asymptomatic carriers of group A streptococci.