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GRANULOCYTE FUNCTION IN PATIENTS WITH MULTIPLE SCLEROSIS
Author(s) -
NœSs A.,
Nyland H.,
Glette J.,
Larsen J. P.,
Rygh T.,
Solberg C. O.
Publication year - 1986
Publication title -
acta pathologica microbiologica scandinavica series c: immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0202
DOI - 10.1111/j.1699-0463.1986.tb02095.x
Subject(s) - granulocyte , opsonin , multiple sclerosis , chemotaxis , immunology , receptor , motility , peripheral blood , medicine , platelet , chemiluminescence , peripheral , function (biology) , phagocytosis , chemistry , biology , microbiology and biotechnology , organic chemistry
Peripheral blood granulocytes and sera from patients with relapsing/remittent (group I) and chronic progressive (group II) multiple sclerosis (MS) did not differ from control cells and sera with regard to 1) the proportion of cells bearing receptors for Fcy and C3b; 2) random or directed (chemotactic) motility of granulocytes; 3) activation as measured by chemiluminescence; 4) opsonic activity of sera. The results of this study suggest that granulocyte function in MS is normal.