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KERATIN PROTEINS IN THE EPITHELIUM OF THE UTERINE CERVIX
Author(s) -
TEGLBJÆRG C. STUBBE,
NORRILD B.,
DABELSTEEN E.
Publication year - 1985
Publication title -
acta pathologica microbiologica scandinavica series a :pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0164
DOI - 10.1111/j.1699-0463.1985.tb03965.x
Subject(s) - keratin , epithelium , uterine cervix , cervix , biology , andrology , medicine , pathology , carcinoma , cancer
Keratin proteins in human cervical squamous epithelium were investigated by the immunofluorescence technique, using the monoclonal keratin antibodies AE1 and AE2. Although the exocervic is covered by a non‐keratinizing, histologically homogenous, squamous epithelium, different staining patterns were found within a single histological section. This indicates a regional variation in the maturation pattern of stratified exocervical epithelium. Detection of morphological versus biochemical keratinization in the diagnosis of pathological cervical conditions is discussed.