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XENO‐ AND AUTO‐PERFUSION OF RABBIT KIDNEY.
Author(s) -
JØRGENSEN KAJ ANKER,
KEMP EJVIND,
BARFORT PER,
STARKLINT HENRIK,
LARSEN SVEND,
JACOBSEN IB ABILDGAARD,
DIEPERINK HANS,
FRIFELT JENS JØRGEN,
MUNKANDERSEN GEORG
Publication year - 1985
Publication title -
acta pathologica microbiologica scandinavica series a :pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0164
DOI - 10.1111/j.1699-0463.1985.tb03955.x
Subject(s) - rabbit (cipher) , perfusion , kidney , medicine , computer science , computer security
Five rabbit kidneys were perfused with human blood and another five with their own blood in a re‐circulating oxygenated system at 37°C. The flow decreased to 2 ml/min. within 30 min. in all xenoperfusions, while none of the autoperfused had decreased to this level by 60 min. Endothelial damage, exudation, and IgG deposits along the basement membrane of the glomerular capillaries were the discrimininative features of the xenoperfusion. In these experiments, we were unable to demonstrate any major role of platelets in the process leading to decreased blood flow.