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GYNECOMASTY: ESTROGEN AND ANDROGEN RECEPTORS. A Clinical‐Pathological Investigation
Author(s) -
POULSEN HANS SKOVGAARD,
HERMANSEN CHRISTIAN,
ANDERSEN JOHAN A.,
ANDERSEN HANS U.,
JENSEN JØRN
Publication year - 1985
Publication title -
acta pathologica microbiologica scandinavica series a :pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0164
DOI - 10.1111/j.1699-0463.1985.tb03946.x
Subject(s) - androgen receptor , pathological , estrogen , estrogen receptor , androgen , receptor , medicine , endocrinology , hormone , prostate cancer , cancer , breast cancer
The histology, estrogen (ER)‐ and androgen (AR)‐ receptor content, s‐FSH, s‐LH, s‐17‐β‐estradiol, U‐17‐ketosteroid and U‐17‐ketogen steroid patterns were measured in a consecutive series of 20 patients operated on for gynecomasty. Two out of 22 specimens were ER‐positive, and 4 out of 22 were AR‐positive. No relationship was demonstrated between the histopathologic features, ie. active – intermediate – inactive gynecomasty, and the steroid receptor content in the present limited number of cases. In addition, there was no marked relationship between the histopathologic features and the hormone values.