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RHEUMATOID ARTHRITIS CELLS IN EXPERIMENTAL PLEURITIS IN MICE
Author(s) -
FAARUP POUL,
FAURSCHOU PETER
Publication year - 1985
Publication title -
acta pathologica microbiologica scandinavica series a :pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0164
DOI - 10.1111/j.1699-0463.1985.tb03943.x
Subject(s) - pleurisy , rheumatoid arthritis , pleural cavity , parietal pleura , medicine , pathology , antigen , rheumatoid nodule , fibrin , immunology , arthritis , lung , pleural effusion , anatomy
In mice immunized with bovine fibrin, the same antigen was applied to the pleural cavity. A granulomatous pleuritis appeared affecting both the visceral and the parietal pleura, especially located around the antigen particle. Rheumatoid arthritis (RA) cells were constantly found in the pleural cavity when pleural lesions were present. This immunological, granulomatous pleuritis is the first experimental model for the study of RA cell‐positive types of pleurisy in humans.