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PRODUCTION AND PARTIAL CHARACTERIZATION OF MONOCLONAL HYBRIDOMA ANTIBODIES TO MYCOBACTERIUM TUBERCULOSIS
Author(s) -
SCHOU C.,
YUAN Z. L.,
ANDERSEN A. B.,
BENNEDSEN J.
Publication year - 1985
Publication title -
acta pathologica microbiologica scandinavica series c: immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0202
DOI - 10.1111/j.1699-0463.1985.tb02955.x
Subject(s) - monoclonal antibody , mycobacterium tuberculosis , tuberculosis , virology , antibody , microbiology and biotechnology , mycobacterium , immunology , biology , medicine , pathology
The production and partial characterization of monoclonal hydridoma antibodies against Mycobacterium tuberculosis is described. 30 clones have been produced. Their reactivity towards M. tuberculosis antigens have been tested in immunoblotting from SDS‐PAGE, in crossed immunoelectrophoresis and in ELISA. The Mab's separated into four reactivity groups, one of which may be relevant in assays for antigen specific for M. tuberculosis.